Pharmaceutical Preparations · SIC 2834

ALNYLAM PHARMACEUTICALS, INC.

ALNY

Watch

Latest revenue

$1.17B

as of 2026-03-31

Latest net income

$206.0M

as of 2026-03-31

Net margin

17.6%

as of 2026-03-31

Price · 5Y

+16.0% / yr 2.2 pts / yr vs S&P 500 109.5% total
Compare:

Live market

delayed ≤15 min
$297.45
1.02%
Market cap
$39.45B
Enterprise value
$39.45B
P/E (trailing)
125.7×
Forward P/E
P/B
Dividend yield
0.0%
52-wk high
$495.55
52-wk low
$284.28
Beta
Shares out
132.6M

5-year trend

About ALNY

Business description and risk factors will appear here once ALNY's latest filing is fully ingested.

Profitability

Operating margin

13.5%

271.7%

Net margin

8.4%

168.3%

Return on equity

39.8%

109.6%

Return on assets

6.3%

196.3%

Leverage

Debt / equity

5.29×

91.5%

Long-term debt / equity

0.00×

100.0%

Debt / assets

84.1%

14.5%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$1.17B+96.4%$206.0M+1228.7%17.6%

Q4 2025

2025-12-31

$1.10B+84.9%$270.9M+423.5%24.7%

Q3 2025

2025-09-30

$1.25B+149.3%$127.3M+214.1%10.2%

Q2 2025

2025-06-30

$773.7M+17.3%$-66.3M-292.4%-8.6%

Q1 2025

2025-03-31

$594.2M+20.2%$-18.3M+72.3%-3.1%

Q4 2024

2024-12-31

$593.2M$-83.8M-14.1%

Q3 2024

2024-09-30

$500.9M-33.3%$-111.6M-175.5%-22.3%

Q2 2024

2024-06-30

$659.8M+107.0%$-16.9M+93.9%-2.6%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

Pharmaceutical Preparations · SIC 2834

No data yet for industry average

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Insider activity

Insider buying

$0

Insider selling

$103.7M

Net activity

−$103.7M

Distinct insiders

9

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2026-04-06

Melissa Mclaughlin

Chief Human Resources Officer

Sale56$320.14$17.9K
2026-04-06

Melissa Mclaughlin

Chief Human Resources Officer

Sale909$329.76$299.8K
2026-04-06

Melissa Mclaughlin

Chief Human Resources Officer

Sale829$330.46$274.0K
2026-04-06

Melissa Mclaughlin

Chief Human Resources Officer

Sale293$331.89$97.2K
2026-04-06

Melissa Mclaughlin

Chief Human Resources Officer

Sale199$333.94$66.5K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale265$316.61$83.9K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale359$317.44$114.0K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale209$318.47$66.6K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale86$319.69$27.5K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale147$320.62$47.1K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale224$321.64$72.0K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale245$322.86$79.1K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale81$323.64$26.2K
2026-04-02

Melissa Mclaughlin

Chief Human Resources Officer

Sale8$325.49$2.6K
2026-03-05

Pushkal Garg

EVP Chief R&D

Sale654$322.33$210.8K
2026-03-05

Pushkal Garg

EVP Chief R&D

Sale740$323.55$239.4K
2026-03-05

Pushkal Garg

EVP Chief R&D

Sale510$324.59$165.5K
2026-03-05

Pushkal Garg

EVP Chief R&D

Sale500$326.08$163.0K
2026-03-05

Kevin Joseph Fitzgerald

CSO & EVP, Head of Research

Sale124$321.81$39.9K
2026-03-05

Kevin Joseph Fitzgerald

CSO & EVP, Head of Research

Sale233$323.25$75.3K
2026-03-05

Kevin Joseph Fitzgerald

CSO & EVP, Head of Research

Sale148$324.60$48.0K
2026-03-05

Kevin Joseph Fitzgerald

CSO & EVP, Head of Research

Sale153$326.24$49.9K
2026-03-04

Pushkal Garg

EVP Chief R&D

Sale106$319.03$33.8K
2026-03-04

Pushkal Garg

EVP Chief R&D

Sale102$320.01$32.6K
2026-03-04

Pushkal Garg

EVP Chief R&D

Sale215$320.81$69.0K
2026-03-04

Pushkal Garg

EVP Chief R&D

Sale289$321.82$93.0K
2026-03-04

Pushkal Garg

EVP Chief R&D

Sale350$323.01$113.1K
2026-03-04

Pushkal Garg

EVP Chief R&D

Sale767$323.84$248.4K
2026-03-04

Pushkal Garg

EVP Chief R&D

Sale272$324.88$88.4K
2026-03-04

Pushkal Garg

EVP Chief R&D

Sale208$325.67$67.7K

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns ALNY

Institutional value

$23.53B

Total shares held

72.0M

Distinct holders

530

As of

2026-03-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1Capital World Investors10.8M$3.57BNew
2BlackRock, Inc.10.4M$3.46BNew
3Capital Research Global Investors9.5M$3.13BNew
4VANGUARD PORTFOLIO MANAGEMENT LLC6.5M$2.15BNew
5JPMORGAN CHASE & CO6.3M$2.00BNew
6VANGUARD CAPITAL MANAGEMENT LLC5.9M$1.97BNew
7BAILLIE GIFFORD & CO2.5M$825.1MNew
8Clearbridge Investments, LLC1.4M$448.7MNew
9Invesco Ltd.1.3M$427.4MNew
10Legal & General Group Plc934.9K$309.3MNew
11VANGUARD FIDUCIARY TRUST CO840.9K$278.2MNew
12DEUTSCHE BANK AG\761.5K$251.9MNew
13FEDERATED HERMES, INC.687.8K$227.6MNew
14UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC677.5K$224.2MNew
15Bank of New York Mellon Corp491.2K$162.5MNew
16FRANKLIN RESOURCES INC470.4K$155.6MNew
17UBS Group AG458.9K$151.8MNew
18Swiss National Bank387.7K$128.3MNew
19DIMENSIONAL FUND ADVISORS LP384.2K$127.1MNew
20FIRST TRUST ADVISORS LP382.7K$126.6MNew

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

Top questions investors are asking

Coming once ALNY's latest filing finishes processing.