Pharmaceutical Preparations · SIC 2834

Aprea Therapeutics, Inc.

APRE

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Latest revenue

as of 2025-12-31

Latest net income

$-12.6M

as of 2025-12-31

Net margin

as of 2025-12-31

5.6
of 10

ActaClear Score

Neutral
#371 of 528 in Pharmaceutical Preparations
+0.1 · 2d
Profitability·25%
4.4
Growth·15%
Value·20%
7.0
Quality·20%
Momentum·20%
5.6

Computed from 5 years of SEC fundamentals + latest market data, ranked within Pharmaceutical Preparations (528 peers). 10 = best in industry, 5 = median, 0 = worst. Refreshed Jun 7, 2026.

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Price · 5Y

-32.2% / yr 51.9 pts / yr vs S&P 500 85.6% total
Compare:

Live market

delayed ≤15 min
$0.75
Market cap
$9.3M
Enterprise value
$-37.2M
P/E (trailing)
Forward P/E
P/B
0.22×
Dividend yield
0.0%
52-wk high
$2.22
52-wk low
$0.55
Beta
Shares out
12.4M

5-year trend

What this company does

AI

You should read the following discussion and analysis of our financial condition and results of operations together with the unaudited financial information and notes thereto included in this Quarterly Report on Form 10-Q. Some of the information contained in this discussion and analysis or set forth elsewhere in this Quarterly Report, including information with respect to our plans and strategy for our business and related financing, including forward-looking statements that involve risks and uncertainties. As a result of many factors, including those factors set forth in the “Risk Factors” section of this Quarterly Report, our actual results could differ materially from the results…

AI summary unavailable — showing raw filing excerpt

Generated from APRE's filing dated 2019-11-14

Key risks

AI

Item 1A. Risk Factors ​ Our business is subject to substantial risks and uncertainties. Investing in our common stock involves a high degree of risk. You should carefully consider the risk factors below together with the information contained elsewhere in this Annual Report on Form 10-K, including Part II, Item 8 “Financial Statements and Supplementary Data” and Part II, Item 7, “Management’s Discussion and Analysis of Financial Condition and Results of Operations,” and in our other public filings in evaluating our business. Any of the risks and uncertainties described below and in our other filings with the SEC, either alone or taken together, could materially and adversely affect our…

AI summary unavailable — showing raw filing excerpt

Generated from APRE's filing dated 2019-11-14

Profitability

Return on equity

-101.3%

50.9%

Return on assets

-79.1%

46.3%

Leverage

Debt / equity

0.28×

16.0%

Debt / assets

21.9%

12.5%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$-3.3M+16.4%

Q4 2025

2025-12-31

$-2.5M+15.2%

Q3 2025

2025-09-30

$-3.0M+21.4%

Q2 2025

2025-06-30

$-3.2M+6.7%

Q1 2025

2025-03-31

$-3.9M-39.9%

Q4 2024

2024-12-31

$-2.9M

Q3 2024

2024-09-30

$-3.8M-18.1%

Q2 2024

2024-06-30

$-3.5M-6.5%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

Pharmaceutical Preparations · SIC 2834

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Insider activity

Insider buying

$210.9K

Insider selling

$0

Net activity

+$210.9K

Distinct insiders

4

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2026-03-31

John P. Hamill

SrVP/CFO/Prin Fin & Acct Ofcr

Purchasederiv.30,978$0.81$25.0K
2026-03-31

John P. Hamill

SrVP/CFO/Prin Fin & Acct Ofcr

Purchasederiv.30,978
2026-03-31

Richard Peters

Director

Purchasederiv.123,915$0.81$100.0K
2026-03-31

Richard Peters

Director

Purchasederiv.123,915
2026-01-30

Oren Gilad

President/CEO

Purchase28,100$0.89$25.0K
2026-01-30

Oren Gilad

President/CEO

Purchasederiv.28,100
2026-01-30

John P. Hamill

SrVP/CFO/Prin Fin & Acct Ofcr

Purchase5,700$0.89$5.1K
2026-01-30

John P. Hamill

SrVP/CFO/Prin Fin & Acct Ofcr

Purchasederiv.5,700
2025-12-10

Marc Duey

Director

Purchase21,459$1.17$25.0K
2025-12-10

Marc Duey

Director

Purchasederiv.21,459
2025-12-10

John P. Hamill

SrVP/CFO/Prin Fin & Acct Ofcr

Purchase5,000$1.17$5.8K
2025-12-10

John P. Hamill

SrVP/CFO/Prin Fin & Acct Ofcr

Purchasederiv.5,000
2025-12-10

Oren Gilad

President/CEO

Purchasederiv.21,459$1.17$25.0K
2025-12-10

Oren Gilad

President/CEO

Purchasederiv.21,459

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns APRE

Institutional value

$884.8K

Total shares held

1.2M

Distinct holders

11

-10 vs prior

As of

2026-03-31

Prior: 2025-12-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1AIGH Capital Management LLC1.0M$774.8K+645.0K (+174.1%)Added
2BNP PARIBAS FINANCIAL MARKETS39.8K$30.4K+12.5K (+45.7%)Added
3VANGUARD FIDUCIARY TRUST CO38.5K$29.3KNew
4LPL Financial LLC21.1K$16.1K-5.0K (-19.2%)Trimmed
5VANGUARD CAPITAL MANAGEMENT LLC19.6K$15.0KNew
6HighTower Advisors, LLC13.9K$10.6K+0 (+0.0%)No change
7BlackRock, Inc.8.5K$6.5K+0 (+0.0%)No change
8UBS Group AG2.2K$1.6K-308 (-12.5%)Trimmed
9GROUP ONE TRADING LLC577$440+0 (+0.0%)No change
10WealthCollab, LLC158$121+0 (+0.0%)No change
11SBI Securities Co., Ltd.16$12+1 (+6.7%)Added

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

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