Pharmaceutical Preparations · SIC 2834

AYTU BIOPHARMA, INC

AYTU

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Latest revenue

$12.4M

as of 2026-03-31

Latest net income

$-5.6M

as of 2026-03-31

Net margin

-45.3%

as of 2026-03-31

7.6
of 10

ActaClear Score

Above avg
#127 of 528 in Pharmaceutical Preparations
new
Profitability·25%
7.5
Growth·15%
8.3
Value·20%
6.9
Quality·20%
8.0
Momentum·20%
7.6

Computed from 5 years of SEC fundamentals + latest market data, ranked within Pharmaceutical Preparations (528 peers). 10 = best in industry, 5 = median, 0 = worst. Refreshed Jun 6, 2026.

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Price · 5Y

-16.2% / yr 35.9 pts / yr vs S&P 500 58.6% total
Compare:

Live market

delayed ≤15 min
$2.20
3.54%
Market cap
$23.6M
Enterprise value
$18.7M
P/E (trailing)
Forward P/E
P/B
0.67×
Dividend yield
0.0%
52-wk high
$3.06
52-wk low
$1.65
Beta
Shares out
10.7M

5-year trend

What this company does

AI

ITEM 1. BUSINESS Company Overview Aytu BioPharma, Inc. (“Aytu,” the “Company,” “we,” “us,” or “our”) is a pharmaceutical company focused on advancing innovative medicines for complex central nervous system diseases to improve the quality of life for patients. We were originally incorporated as Rosewind Corporation on August 9, 2002, in the state of Colorado and re-incorporated as Aytu BioScience, Inc. in the state of Delaware on June 8, 2015. In March 2021, we changed our name to Aytu BioPharma, Inc. Our common stock trades on the Nasdaq Capital Market LLC (the “Nasdaq”) under the ticker symbol “AYTU.” Our principal office is located at 7900 East Union Avenue, Suite 920, Denver, Colorado…

AI summary unavailable — showing raw filing excerpt

Generated from AYTU's filing dated 2025-09-23

Key risks

AI

ITEM 1A. RISK FACTORS Investing in our securities includes a high degree of risk. You should consider carefully the specific factors discussed below, together with all of the other information contained in this Annual Report. If any of the following risks actually occurs, our business, financial condition, results of operations and future prospects would likely be materially and adversely affected. This could cause the market price of our securities to decline and could cause you to lose all or part of your investment. Risks Related to Our Business and Financial Position We have incurred losses to date and can give no assurance of profitability. ​ We have incurred losses in each year since…

AI summary unavailable — showing raw filing excerpt

Generated from AYTU's filing dated 2025-09-23

Profitability

Gross margin

69.0%

2.5%

Operating margin

-11.8%

81.8%

Net margin

-20.4%

4.4%

Return on equity

-71.5%

25.1%

Return on assets

-10.9%

18.6%

Leverage

Debt / equity

5.55×

70.1%

Long-term debt / equity

0.57×

46.4%

Debt / assets

84.7%

10.7%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$12.4M-32.7%$-5.6M-240.7%-45.3%

Q4 2025

2025-12-31

$15.2M-6.5%$-8.6M-1193.8%-56.8%

Q3 2025

2025-09-30

$13.9M-16.2%$2.0M+33.3%14.1%

Q2 2025

2025-06-30

$15.1M-50.2%$-19.8M-329.2%-130.9%

Q1 2025

2025-03-31

$18.5M+31.6%$4.0M+238.3%21.6%

Q4 2024

2024-12-31

$16.2M-13.5%$788.0K+458.2%4.9%

Q3 2024

2024-09-30

$16.6M-7.0%$1.5M+118.2%8.9%

Q2 2024

2024-06-30

$30.4M$-4.6M-15.2%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

Pharmaceutical Preparations · SIC 2834

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Insider activity

Insider buying

$125.0K

Insider selling

$0

Net activity

+$125.0K

Distinct insiders

2

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2025-06-09

Jarrett Disbrow

Chief Business Officer

Purchase16,666$1.50$25.0K
2025-06-09

Joshua R. Disbrow

Chief Executive Officer

Purchase66,666$1.50$100.0K

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns AYTU

Institutional value

$1.4M

Total shares held

659.8K

Distinct holders

19

-19 vs prior

As of

2026-03-31

Prior: 2025-12-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1VANGUARD CAPITAL MANAGEMENT LLC261.1K$712.9KNew
2Persistent Asset Partners Ltd92.9K$253.6K+13.5K (+17.0%)Added
3VANGUARD FIDUCIARY TRUST CO47.0K$128.4KNew
4DIMENSIONAL FUND ADVISORS LP43.6K$119.0K+8.2K (+23.3%)Added
5BELLEVUE ASSET MANAGEMENT, LLC25.0K$68.3K+0 (+0.0%)No change
6BlackRock, Inc.22.8K$62.2K+0 (+0.0%)No change
7Daytona Street Capital LLC10.0K$26.8K+0 (+0.0%)No change
8UBS Group AG1.7K$4.5K-1.4K (-45.5%)Trimmed
9JPMORGAN CHASE & CO154$405New
10CROWN ADVISORS MANAGEMENT, INC.145.0K$395New
11WELLS FARGO & COMPANY/MN127$347+0 (+0.0%)No change
12GROUP ONE TRADING LLC37$101+0 (+0.0%)No change
13BNP PARIBAS FINANCIAL MARKETS23$63+0 (+0.0%)No change
14SBI Securities Co., Ltd.11$30+0 (+0.0%)No change
15ACADIAN ASSET MANAGEMENT LLC10.2K$27+0 (+0.0%)No change
16VISION FINANCIAL MARKETS LLC2$6+0 (+0.0%)No change
17Caitong International Asset Management Co., Ltd2$5New
18TSFG, LLC1$0+0 (+0.0%)No change
19FNY Investment Advisers, LLC90$0-31.5K (-99.7%)Trimmed

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

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