In Vitro & In Vivo Diagnostic Substances · SIC 2835

Celldex Therapeutics, Inc.

CLDX

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Latest revenue

$15.0K

as of 2026-03-31

Latest net income

$-78.7M

as of 2026-03-31

Net margin

-524566.7%

as of 2026-03-31

Price · 5Y

+1.9% / yr 11.8 pts / yr vs S&P 500 9.9% total
Compare:

Live market

delayed ≤15 min
$30.73
0.49%
Market cap
$2.41B
Enterprise value
$2.41B
P/E (trailing)
Forward P/E
P/B
Dividend yield
0.0%
52-wk high
$35.79
52-wk low
$18.55
Beta
Shares out
78.5M

5-year trend

What this company does

AI

Item 1. BUSINESS Overview Celldex Therapeutics, Inc., which we refer to as “Celldex,” “we,” “us,” “our” or the “Company,” is a biopharmaceutical company dedicated to exploring the science of mast cell biology and developing therapeutic antibodies which have the ability to engage the human immune system and/or directly affect critical pathways to improve the lives of patients with severe inflammatory, allergic, autoimmune and other devastating diseases. Our drug candidates include monoclonal and bispecific antibodies designed to address mast cell mediated diseases for which available treatments are inadequate. We are focusing our efforts and resources on the continued research and…

AI summary unavailable — showing raw filing excerpt

Generated from CLDX's filing dated 2026-02-25

Key risks

AI

Item 1A. RISK FACTORS You should consider carefully these risk factors together with all of the information included or incorporated by reference in this Annual Report in addition to our financial statements and the notes to our financial statements. This section includes forward-looking statements. The following is a discussion of the risk factors that we believe are material to us at this time. These risks and uncertainties are not the only ones facing us, and there may be additional matters that we are unaware of or that we currently consider immaterial. All of these could adversely affect our business, results of operations, financial condition and cash flows. Summary of Risk Factors…

AI summary unavailable — showing raw filing excerpt

Generated from CLDX's filing dated 2026-02-25

Profitability

Operating margin

-18599.8%

569.3%

Net margin

-16748.0%

644.8%

Return on equity

-49.1%

132.3%

Return on assets

-44.4%

122.8%

Leverage

Debt / equity

0.11×

74.5%

Debt / assets

9.6%

67.3%

Earnings tracker

QuarterRevenueYoYNet incomeYoYNet margin

Q1 2026

2026-03-31

$15.0K-97.8%$-78.7M-46.3%-524566.7%

Q4 2025

2025-12-31

$-1.3M-211.0%$-81.3M

Q3 2025

2025-09-30

$1.4M-55.4%$-67.0M-59.2%-4708.1%

Q2 2025

2025-06-30

$730.0K-70.8%$-56.6M-57.9%-7753.4%

Q1 2025

2025-03-31

$695.0K+345.5%$-53.8M-7740.4%

Q4 2024

2024-12-31

$1.2M

Q3 2024

2024-09-30

$3.2M+110.3%$-42.1M-1320.0%

Q2 2024

2024-06-30

$2.5M+832.1%$-35.8M-1434.8%

Year-over-year change vs the same fiscal quarter one year prior. Revenue + net income sourced from SEC 10-Q / 10-K filings — no analyst-consensus dependency.

Industry trend

In Vitro & In Vivo Diagnostic Substances · SIC 2835

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Insider activity

Insider buying

$0

Insider selling

$1.3M

Net activity

−$1.3M

Distinct insiders

2

Open-market trades over the last 365 days.

Recent transactions

DateInsiderTypeSharesPriceValue
2025-12-04

Freddy A. Jimenez

SVP & GENERAL COUNSEL

Sale4,166$29.09$121.2K
2025-11-13

Richard M. Wright

Sale49,298$24.00$1.2M
2025-08-13

Freddy A. Jimenez

SVP & GENERAL COUNSEL

Sale341$23.95$8.2K
2025-08-13

Freddy A. Jimenez

SVP & GENERAL COUNSEL

Sale430$25.41$10.9K

Source: SEC Form 4 filings. Officers, directors, and 10%+ owners must disclose share transactions within two business days. RSU grants and tax-withholding rows are excluded by default — compensation activity is not a trading signal.

Who owns CLDX

Institutional value

$533.8M

Total shares held

17.0M

Distinct holders

113

-73 vs prior

As of

2026-03-31

Prior: 2025-12-31

Filers with $100M+ AUM disclose holdings 45 days after quarter end.

Top institutional holders

#ManagerSharesValueQoQ changeAction
1BlackRock, Inc.5.4M$170.3M-81.9K (-1.5%)Trimmed
2VANGUARD CAPITAL MANAGEMENT LLC3.0M$93.9MNew
3DIMENSIONAL FUND ADVISORS LP1.1M$33.6M+407.8K (+62.6%)Added
4Fisher Asset Management, LLC1.0M$32.2M+76.5K (+8.2%)Added
5Pictet Asset Management Holding SA923.7K$29.3M-44.9K (-4.6%)Trimmed
6VANGUARD PORTFOLIO MANAGEMENT LLC629.3K$20.0MNew
7VANGUARD FIDUCIARY TRUST CO429.6K$13.6MNew
8TSP Capital Management Group, LLC375.1K$11.9M+0 (+0.0%)No change
9KENNEDY CAPITAL MANAGEMENT LLC352.3K$11.2MNew
10UBS Group AG297.0K$9.4M-29.5K (-9.0%)Trimmed
11Candriam S.C.A.278.9K$8.8MNew
12CITIGROUP INC217.3K$6.9M+202.4K (+1356.5%)Added
13Nuveen, LLC201.9K$6.4M+1.3K (+0.6%)Added
14Bank of New York Mellon Corp190.4K$6.0M-4.2K (-2.1%)Trimmed
15Connor, Clark & Lunn Investment Management Ltd.184.1K$5.8M+65.9K (+55.7%)Added
16Mirador Capital Partners LP178.1K$5.6M+7.4K (+4.3%)Added
17BNP PARIBAS FINANCIAL MARKETS175.8K$5.6M-54.9K (-23.8%)Trimmed
18JPMORGAN CHASE & CO164.8K$4.9M-8.9K (-5.1%)Trimmed
19Assenagon Asset Management S.A.146.5K$4.6MNew
20DEUTSCHE BANK AG\143.0K$4.5M+6.6K (+4.8%)Added

Source: SEC Form 13F-HR. Positions aggregated across sub-managers within each firm. Options (puts/calls) excluded — common stock only.

Top questions investors are asking

Coming once CLDX's latest filing finishes processing.